产品货号：
Z33992
中文名称：
SDHA抗体
英文名称：
Anti-SDHA Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SDHA Antibody |
| 指标别名 | FP;SDH2;SDHA;SDHF |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF |
| 基因名称 | SDHA |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human SDHA |
| 实际分子量 | 72KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Complex II of the mitochondrial respiratory chain,also known as succinate dehydrogenase or succinate:ubiquinone oxidoreductase,consists of 4 nuclear-encoded polypeptides,these are the flavoprotein subunit (SDHA),the iron sulfur protein subunit (SDHB),and the integral membrane protein subunits SDHC and SDHD.SDHA is an acronym for succinate dehydrogenase complex subunit A.The succinate dehydrogenase (SDH) protein complex catalyzes the oxidation of succinate (succinate + ubiquinone => fumarate + ubiquinol).The SDHA subunit is connected to the SDHB subunit on the hydrophilic,catalytic end of the complex,and weighs 72.7 kDA.Mutations in the SDHA subunit have a distinct pathology from mutations in the SDHB/SDHC/SDHD subunits;it is the only subunit to never have shown tumor suppressor behaviour.Heterozygous carriers of an SDHA mutation do not develop paragangliomas as has been seen for mutations in the other subunits.This appears to be due to the expression of two similar SDHA genes (Types I and II) in the paraganglia system. |
| Uniprot ID | P31040 |
| 基因名全称 | Succinate dehydrogenase [ubiquinone] flavoprotein subunit,mitochondrial |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:20～100ICC/IF Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20～100 |
相关搜索：SDHA抗体，SDHA单抗，Anti-SDHA Antibody